Connect with Dom:
About the Guest:
Dom Messerli, MBA
Founder, President and CEO of Lenoss Medical
Dom Messerli is the visionary Founder, President, and CEO of Lenoss Medical, pioneering biologic technology for the physiological treatment of osteoporotic spinal column fractures.
Prior to founding Lenoss Medical, as Director of R&D, Dom led efforts in the acquisition, integration, and transformation of Johnson & Johnson’s Spine organization, DePuy Synthes Spine. Prior to JNJ, Dom held leadership positions across Product Development and Marketing during the growth of Synthes Spine to over $0.5B in revenue.
With his advanced leadership skills to develop high-performing, collaborative teams, Dom has led global teams through multiple product commercialization launches and successfully led his division from early initiation to a strong market leadership position with an impressive cadence of innovative and successful product introductions, increasing global annual sales from $10M to $150M.
With a philosophy that ingenuity lies in simplicity, Dom the inventor can be found on many relevant patents related to medical devices currently in use across spine specialties. Dom received his Bachelor of Science in Mechanical Engineering degree from the University of Bern in Switzerland and an Executive MBA from Penn State University with admission to the international honor society for collegiate schools of business, Beta Gamma Sigma. Currently, Dom serves on the Board of Directors for RI Bio and is the Chairman of the Board for Lenoss Medical.
Dom is an avid sailor and enjoys sailing in Narraganset Bay.
About the Episode:
For this episode of Entrepreneur Rx, John sits down with Dom Messerli, the President and CEO of Lenoss Medical. Lenoss Medical is disrupting the treatment of spinal fractures with their OsteoPearl Vertebral Body Augmentation (VBA) System. This minimally invasive and epoxy-free technology delivers a fully biological solution to stabilize spinal fractures and utilizes the natural healing properties of healthy bone.
The episode starts off with Dom explaining his background in mechanical engineering and his rise within Synthes, a company specializing in spine technology that was later acquired by Johnson & Johnson. He discusses the inspiration behind Lenoss Medical’s innovative implant, the OsteoPearl, which treats spinal fracture and allows for bone healing as opposed to the current stand of care.
Dom goes on to speak about the shortcomings of traditional kyphoplasty using epoxy (such as complications like intravenous embolism) and points out the advantages of Lenoss Medical’s OsteoPearl implants. He emphasizes that bone materials do not carry the risk of rejection like organ transplants because they contain no living cells.
John and Dom then move to talk about the business side of Lenoss Medical, including raising funds, startup valuation, and the importance of networking in entrepreneurship. They conclude the podcast discussing Dom’s tips for people who want to become an entrepreneur where Dom touches on the importance of partnership.
Entrepreneur Rx Episode 84:
About Lenoss Medical:
Lenoss Medical is disrupting the conventional landscape of osteoporotic vertebral compression fracture treatment, which uses epoxy to stabilize the fractured vertebral body. The OsteoPearl Vertebral Body Augmentation (VBA) System introduces a minimally invasive, biological, and epoxy-free solution, offering immediate stabilization to the fractured vertebral body while fostering a natural environment for fracture healing to occur.
- Discover the innovative OsteoPearl implant by Lenoss Medical and why it could be the new standard of care for treating vertebral compression fractures.
- Gain insights on why new bone formation with the OsteoPearl is a huge plus for patients.
- Understand how asking for the correct valuation is critical to securing funding.
- Be inspired to jump into healthcare entrepreneurship, even if you do not have a traditional healthcare background.
- Learn from Dom’s entrepreneurial experience so that you can lessen some challenges you will face.
- Network with Dom Messerli on LinkedIn to gain more insights to Lenoss Medical and entrepreneurship.
- Visit Lenoss Medical’s website to explore their pioneering biologic technology for the treatment of vertebral compression fractures.
- Follow Lenoss Medical on LinkedIn to stay up to date with their company.
- Listen to Dr. Joseph Lane explain why he is a champion for using the OsteoPearl to treat vertebral compression fractures.
- Watch this short video on the OsteoPearl to get a better understanding of what it is.
- Listen to Dom speak more about Lenoss Medical on Angel Invest Boston’s podcast.
- To connect to Lenoss Medical directly, email firstname.lastname@example.org.
00:00:05 – Introduction to Lenoss Medical
John Shufeldt introduces Dom Messerli, the president and CEO of Lenos Medical, a biologic technology company for treating vertebral compression fractures. Dom shares his background in mechanical engineering and his experience with spinal technologies.
00:03:41 – Innovation of OsteoPearl Implant
Dom explains how the idea for the OsteoPearl implant was born out of the need for better treatment for spinal compression fractures. He describes the benefits of using allograft tissue and the challenges with current epoxy-based treatments.
00:07:44 – Risks and Benefits of OsteoPearl Implant
Dom discusses the risks associated with epoxy-based treatments, including the potential for the epoxy to escape into the bloodstream. He also explains the lack of rejection risk with the OsteoPearl implant due to its natural bone composition.
00:10:33 – Bone Formation and Post-Procedure Recovery
Dom explains the timeline for bone formation and fusion with the OsteoPearl implant, highlighting the stability it provides immediately after the procedure. He also notes that the post-procedure recovery protocol is like that of epoxy-based treatments.
00:12:42 – Overcoming Challenges and Future Outlook
Dom shares the challenges he faced in licensing the technology from a larger organization and forming a partnership with a tissue bank. He expresses confidence in the clinical use of the OsteoPearl implant and its potential to replace epoxy-based treatments.
00:13:39 – Milestones in Medical Entrepreneurship
Dom discusses reaching a major milestone in getting their product into clinics, with 49 cases completed and expanding. Zero intravenous embolism cases have occurred which is a significant achievement.
00:14:28 – The Standard of Care
Dom and John discuss the potential for the OsteoPearl to become the standard of care in medical procedures, given its success in preventing embolism compared to the current standard of care.
00:15:30 – Risks and Complications
The conversation delves into the risks and complications associated with the leakage of epoxy into the heart, lungs, and spinal canal, highlighting the urgent need for a safer alternative.
00:17:42 – Fundraising and Valuation
Dom shares his experience in fundraising, the challenges of asking for money, and the importance of networking. He also discusses the valuation of their company and the impact of the economic environment on their expectations.
00:20:23 – The Grit of Entrepreneurship
Dom emphasizes the challenging nature of entrepreneurship, highlighting the pressure, financial strain, and uncertainty. He also acknowledges the addictive quality of entrepreneurship for those who are truly passionate about it.